Rebellion
Jeremiah 11:10-11 They are turned back to the iniquities of their forefathers, which refused to hear my words; and they went after other gods to serve them: the house of Israel and the house of Judah have broken my covenant which I made with their fathers. 11Therefore thus saith Yahuweh, Behold, I will bring evil upon them, which they shall not be able to escape; and though they shall cry unto me, I will not hearken unto them.
When we walk not in fellowship with God and continue in iniquity; Psalm 66:18 If I regard iniquity in my heart, the Lord will not hear me: John 9:31; James 4:3
Where there is godless living (Galatians 6:19-2119Now the works of the flesh are manifest, which are these; Adultery, fornication, uncleanness, lasciviousness, 20Idolatry, witchcraft, hatred, variance, emulations, wrath, strife, seditions, heresies, 21Envyings, murders, drunkenness, revellings, and such like: of the which I tell you before, as I have also told you in time past, that they which do such things shall not inherit the kingdom of God.) lack of concern for others in their need (Isaiah 58:6-9 6Is not this the fast that I have chosen? to loose the bands of wickedness, to undo the heavy burdens, and to let the oppressed go free, and that ye break every yoke?   7Is it not to deal thy bread to the hungry, and that thou bring the poor that are cast out to thy house? when thou seest the naked, that thou cover him; and that thou hide not thyself from thine own flesh? 
8Then shall thy light break forth as the morning, and thine health shall spring forth speedily: and thy righteousness shall go before thee; the glory of the LORD shall be thy rereward.  9Then shalt thou call, and the LORD shall answer; thou shalt cry, and he shall say, Here I am. If thou take away from the midst of thee the yoke, the putting forth of the finger, and speaking vanity;), and carelessness with regard to the clear instructions of the Word of God. God will not answer your prayers. You stand in the path of divine chastisement. He will correct you according to the new covenant. Job 33:15-28 15In a dream, in a vision of the night, when deep sleep falleth upon men, in slumberings upon the bed; 16Then he openeth the ears of men, and sealeth their instruction,  17That he may withdraw man from his purpose, and hide pride from man.  18He keepeth back his soul from the pit, and his life from perishing by the sword. 
19He is chastened also with pain upon his bed, and the multitude of his bones with strong pain: 20So that his life abhorreth bread, and his soul dainty meat.  21His flesh is consumed away, that it cannot be seen; and his bones that were not seen stick out. 22Yea, his soul draweth near unto the grave, and his life to the destroyers. 23If there be a messenger with him, an interpreter, one among a thousand, to shew unto man his uprightness: 24Then he is gracious unto him, and saith, Deliver him from going down to the pit: I have found a ransom.  25His flesh shall be fresher than a child’s: he shall return to the days of his youth:  26He shall pray unto God, and he will be favourable unto him: and he shall see his face with joy: for he will render unto man his righteousness. 27He looketh upon men, and if any say, I have sinned, and perverted that which was right, and it profited me not;  28He will deliver his soul from going into the pit, and his life shall see the light. 
Hall lu YAH